21 nights · Ocean cruise

21 Night Eastern Caribbean and Panama Canal U.S. Virgin Islands

Aboard Nieuw Amsterdam with Holland America Line

Nights: 21
Departs: Ft. Lauderdale
Sailings: 2
From: $2,554

Check price on CruiseDirect (opens in a new tab) See 2 sailings

21 Night Eastern Caribbean and Panama Canal U.S. Virgin Islands aboard Nieuw Amsterdam

Itinerary

11 ports, in calling order

Day 1 Ft. Lauderdale ship schedule Embark
Days 2–3At sea
Day 4 St John's ship schedule
Day 5 Charlotte Amalie ship schedule
Day 6 Road Town ship schedule
Day 7 San Juan, Puerto Rico ship schedule
Day 8At sea
Day 9 Half Moon Cay ship schedule
Day 10 Ft. Lauderdale ship schedule
Day 11 Half Moon Cay ship schedule
Days 12–13At sea
Day 14 Oranjestad ship schedule
Day 15At sea
Day 16 Cartagena ship schedule
Day 17 Colon ship schedule
Day 18 Puerto Limon ship schedule
Day 19At sea
Day 20 Georgetown ship schedule
Day 21At sea
Day 22 Ft. Lauderdale ship schedule Disembark

Day by day as published by Holland America Line for the Jan 29, 2027 sailing, checked Oct 3. Lines can change a call; confirm before booking excursions.

Upcoming sailings

Lowest fares in US dollars by cabin, refreshed every Monday, last on Nov 2, 2026. Pick a date and we will confirm the live price.

Sailings of 21 Night Eastern Caribbean and Panama Canal U.S. Virgin Islands with fares by cabin
Departs	Inside	Oceanview	Balcony	Suite	Enquire
Fri, Jan 29, 2027to Feb 19	$2,639	$2,819	$4,889	—	Check price departing Jan 29, 2027 on CruiseDirect (opens in a new tab)Price alert for the Jan 29, 2027 departure
Fri, Mar 12, 2027to Apr 2	$2,554	$2,864	$4,214	$7,274	Check price departing Mar 12, 2027 on CruiseDirect (opens in a new tab)Price alert for the Mar 12, 2027 departure